Home > Biology > Detail
search_icon
Question

Describe the function and purpose of the Na+/K+ pump in re-establishing the resting membrane potential?

Answer

Na+/K+ pump maintains the concentration gradient of sodium (Na+) and potassium (K+) ions across the plasma membrane and restores the resting membrane potential after nerve impulses. The Na+/K+ pump mechanism involves three sodium ions binding to the pump on the inside of the cell. ATP is split into ADP and a phosphate ion. The phosphate ion attaches to the pump causing a conformational change, ejecting the sodium ions to the outside of the cell. Two potassium ions from outside the cell bind to the pump. The phosphate ion detaches from the pump and restores the original conformation. The potassium ions are released into the cell.

  • Q:What is the resting membrane potential? A:The resting membrane potential is the electrical charge difference that exists across the plasma membrane of cells.
  • Q:What is the role of Na+/K+ pump in maintaining the resting membrane potential? A:Na+/K+ pump is responsible for maintaining the concentration gradient of sodium (Na+) and potassium (K+) ions across the plasma membrane and restoring the resting membrane potential after nerve impulses.
  • Q: What are the steps involved in the Na+/K+ pump mechanism? A:1) Three sodium ions (Na+) bind to the pump on the inside of the cell. 2) ATP is split into ADP and a phosphate ion. 3) The phosphate ion attaches to the pump causing a conformational change, ejecting the sodium ions to the outside of the cell. 4) Two potassium ions (K+) from outside the cell bind to the pump. 5) The phosphate ion detaches from the pump, restoring the original conformation. 6) The potassium ions are released into the cell.